The 2 Biggest Factors That Influence Aging, According to Research
Aging is a complex process shaped by various lifestyle choices and environmental conditions. While genetics play a role, new research highlights that certain external factors have a much more significant impact on biological aging. A large-scale study analyzed data from nearly half a million individuals and pinpointed the two most influential factors—smoking and socioeconomic status.
This study offers a deeper understanding of how everyday habits and living conditions contribute to aging, disease risks, and overall life expectancy.
How Environmental Factors Shape Aging
Researchers examined 164 different lifestyle and environmental elements to assess their impact on aging and age-related diseases. The study utilized an advanced tool known as an “aging clock” to estimate biological aging based on molecular markers in the body rather than chronological age.
One of the lead researchers explained that previous studies hinted at the dominant role of environmental factors over genetics in aging. However, this research provided concrete data to support that idea. By focusing on external exposures, scientists were able to evaluate their direct influence on lifespan and health outcomes.

Freepik | Smoking and socioeconomic status emerged as the leading determinants of aging.
The Role of an Aging Clock
The aging clock used in this study measures biological age by analyzing proteins in the blood. Unlike traditional methods that rely on birth years, this model provides a more accurate picture of internal aging. The researchers determined that the aging clock effectively predicts future health risks, mortality rates, and the likelihood of developing multiple chronic diseases.
To ensure the validity of their findings, they only included factors that showed a consistent association between aging and mortality. Any conflicting data—where a factor seemed to accelerate aging but decrease mortality risk or vice versa—was excluded from the study.
Smoking and Socioeconomic Conditions
Among the 25 factors linked to aging and mortality, 23 were considered modifiable. The study highlighted the most impactful influences, including:
1. Smoking habits
2. Income and financial stability
3. Physical activity levels
4. Housing conditions
5. Education and employment status
6. Sleep patterns and tiredness frequency
Smoking was found to be the most damaging factor, correlating with 21 different diseases. Meanwhile, financial struggles and lower socioeconomic status were linked to 19 health conditions. The findings emphasize that fundamental aspects of daily life significantly impact longevity—often more than trendy wellness interventions.
Health Risks Tied to Environmental Exposures
The study revealed that environmental factors account for 17% of variations in mortality risk, whereas genetics only explain about 2%. The strongest associations were seen in diseases affecting the lungs, heart, and liver. In contrast, genetic predisposition remained the primary risk factor for conditions like dementia and breast cancer.
One of the researchers stated that these findings reinforce the importance of lifestyle and policy interventions. Unlike genetics, environmental influences are largely within human control, offering opportunities to enhance overall health and lifespan.
More Research Needed to Identify Additional Aging Factors

Freepik | Environmental aging risks demand more research, especially on chemical exposures.
While this study provided valuable insights, experts believe there are still many unidentified environmental risks affecting aging. Future research may explore additional exposures, such as chemical pollutants, and assess their contribution to age-related health issues.
A cardiologist who reviewed the findings pointed out that while the study confirms what medical professionals have long suspected, it also highlights the need for preventive measures. He noted that addressing modifiable lifestyle factors could significantly reduce the global disease burden.
A Step Toward Healthier Aging
The research underscores the fact that aging isn’t solely dictated by genetics. Lifestyle choices, financial stability, and living conditions play a crucial role in determining how the body ages. Scientists suggest that public health efforts should focus on reducing harmful exposures and improving economic conditions to enhance overall well-being.
Preventative measures—such as smoking cessation programs, increased physical activity, and improved access to healthcare—can make a significant difference. Additionally, integrating genetic and environmental data could lead to more personalized approaches to longevity and disease prevention.
By recognizing the power of external influences, individuals and policymakers alike can work toward healthier, longer lives.